EBOLA VIRUS DISEASE: A DISEASE WITH NO SPECIFIC CURE

Abstract

Ebola virus disease is an infectious virus-based disease that spreads through human-to human contacts. The first human case was found in 1967, in Germany, the patient was a scientist working in a lab with monkeys that were imported from the Uganda region. The first outbreak of this disease was found in 1976 in the Africa region near the Ebola River, Republic of Congo. Major symptoms of this disease are normal “flu-like” in its primary stage such as fever, coughing, headache, and diarrhea. As the disease progresses the symptoms get worsen. The treatment options for this disease are very limited. Many vaccines are found to be effective against the Ebola virus disease such as the chad3 vaccine, rVSVZEBOV vaccine, MVA-BN-Filoã vaccine, ERVEBO vaccine, there are many treatment options therapies such as Janssen Ebola prevention vaccine therapy, combination therapy (2014), EBANGA treatment, etc. Recently in 2019 US-FDA has approved another vaccine as the treatment option for Ebola virus disease. The basic supportive care system Is also found to be very helpful in the treatment of the disease. Some medications are still under investigation for their effectiveness against the Ebola virus such as Remdesivir, Favipiravir, Quinacrine, Tilorone. Some studies were done to compare the effectiveness of newly found drugs against Ebola virus disease which were known as PALM studies. Here In this review, we are going to look at all the possible treatment options and vaccines that are effective.
against Ebola virus disease.