LIPID MICROSPHERES: EMERGING TRENDS IN PHARAMCEUTICAL TECHNOLOGY

Authors

  • Dhiren P. Shah Shree N L Patel College of Pharmacy, Umarakh, Bardoli. Gujarat

DOI:

https://doi.org/10.5281/

Keywords:

Lipid microsphere (LM), Solubility, surface charge and surface legands

Abstract

Recent advances in the isolation techniques, medicinal chemistry, biotechnology and the capacity for screening new drug compounds have been able to produce several lead molecules. More than likely many potential drugs have lost because of inadequate formulation strategies during different stages of evaluation. In many cases, the loss could have been due to solubility problems. To maximize the drug potential of all molecules, there has been a renewed effort to find formulation strategies for compounds inadequately soluble in water. Many different drug delivery systems for lipid soluble compounds have been suggested, but lipid microsphere (LM) drug delivery system has great potential. The system is time tested, safe and stable at room temperature, easily mass- produced yet cheaper. The drug distribution and targeting can be achieved by manipulating size, surface charge and surface legands of LM. At present, commercially available lipid microsphere formulation are few but in future this system will find considerable share in the market.

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Published

31-12-2019

Issue

Section

Research Articles

How to Cite

LIPID MICROSPHERES: EMERGING TRENDS IN PHARAMCEUTICAL TECHNOLOGY. (2019). Nirma University Journal of Pharmaceutical Sciences, 6(2), 11-34. https://doi.org/10.5281/